New coronavirus aerosol sampling and rapid detection solution

1. Situation of new coronavirus pneumonia

At the end of 2019, a new coronavirus pneumonia broke out in Wuhan, Hubei, and tens of thousands of confirmed cases of infection have been reported in a short period of time. The new crown epidemic situation is raging. The nationwide prevention and control of the epidemic situation and the fight against the "war epidemic" have affected millions of people. The spread and detection of the new coronavirus have become issues of concern to everyone.

Second, the virus transmission


At 2:00 pm on February 8, 2020, a news conference was held in Shanghai. Health and anti-epidemic experts emphasized that the currently available routes for pneumonia infection of new coronavirus infections are direct transmission, aerosol transmission and contact transmission.


Direct transmission refers to infections caused by the patient's sneezing, coughing, talking droplets, and exhaled gas inhaled directly;


Aerosol transmission refers to the mixing of droplets in the air to form an aerosol, which causes infection after inhalation;


Contact transmission refers to the deposition of droplets on the surface of objects, contact with contaminated hands, and then contact with the mucous membranes of the mouth, nose, eyes, etc., resulting in infection.


3. The composition of biological aerosol in the air


Aerosols in the air include viruses (influenza, measles, chickenpox), bacteria (chlamydia, mycobacterium tuberculosis, legionella) and fungi.


Different types of pathogenic microorganisms form bioaerosols of different sizes, which can be roughly divided into the following categories: 0.02 to 0.3 microns viruses, 0.5 to 10 microns bacteria and 0.5 to 30 microns fungi, as well as allergens and pollen, etc. .


Bioaerosols may exist in different forms: microbial residues; single virus or fungal spores, bacterial cells or spores; aggregates of several single cells, spores or viruses; or attachment to other non-biological particles.


4. Significance of virus aerosol sampling and rapid detection


The propagation distance of aerosol is far, can reach tens of meters, or even hundreds of meters, far exceeding the propagation distance of droplets. The World Health Organization (WHO) report pointed out that viruses or bacteria can spread through aerosols over long distances and cause large-scale infections in a short period of time.


In view of the transmission characteristics of virus aerosols, sampling and rapid detection of the air environment to determine the degree of virus aerosol pollution in the air in key areas such as hospital outpatients, wards, contaminated areas, buffer zones, and safety areas are of great importance for protecting the health of workers. Important significance: Sampling and testing the air environment, and further studying the law of virus aerosol transmission are of great significance for the prevention and control of virus transmission.


5. Virus aerosol sampling and rapid detection solution


Since there is currently no technology and detection equipment for directly detecting virus aerosols, but the equipment and technology for detecting viruses in liquids is mature, the current method for detecting virus aerosols is mainly to use biological aerosol samplers to collect virus particles in the air Into the liquid, and then use the existing liquid detection equipment to detect the collected sample liquid, and then determine whether the air contains the detected virus aerosol. Viral aerosols currently use a combination of liquid-phase aerosol collection equipment and nucleic acid detection equipment for sampling and rapid detection.


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